Seduced by My Best Friend
Oshimeter
Synopsis
Shion and Rui are college guys and best friends who spend their free time picking up women together, until a mysterious drug handed to Shion by a stranger completely upends that arrangement. He wakes up the next morning in a woman's body, and before he can figure out what happened, Rui meets his transformed friend without recognizing him. Things get complicated fast. The series is an 8-episode ONA from Elias, with each episode running around 6 minutes, so the whole thing goes by quickly. It leans into the awkward comedy of Shion navigating a body that isn't his, while also being honest that this is Boys Love with explicit content. don't go in expecting anything tame. What makes it interesting is that the gender-swap isn't just a gimmick. It genuinely reshapes how these two interact and what their friendship means. If you've seen Kashimashi: Girl Meets Girl or Kämpfer and liked the gender transformation angle, this covers similar territory but filters it through a Boys Love lens, which gives it a different emotional texture. Fans of that niche will probably find the premise clicks in a way that feels fresh. It's a short commitment, the setup is specific enough to hook you in the first episode, and it does not try to be something it isn't.
Episode Guide
Characters
Rui Chihaya
Furukawa Makoto
MANGA BRIDGE
This season covers Chapters 1-5 of the manga. Continue reading from Chapter 1.

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That curse from the girl Shion rejected really came back to haunt him in the most literal way possible and watching him struggle in a dress was gold
I found it so funny how Shion spent his whole life hitting on girls, but now he is the one getting chased by his own best friend.
Nonsense plot logic like that mystery drug makes it hard to take the story seriously and you just have to turn your brain off
I can not believe the professor just accepted the magical curse explanation without asking a single question and it made me laugh so hard
Rui hitting on Shion before he even realizes it is his best friend is so messy and the timing was actually wild
The transition from them being bros to Rui pinning Shion down was so fast and the fact that they are both technically guys makes the whole setup way more interesting than a typical romance
Watching a guy go from being a player to being the one getting played by his best friend is a funny premise but the clunky animation during the spicy parts really kills the mood
I really didn't expect the kuro-gyaru look for Shion but it actually works and the whole vibe feels so much like a classic yaoi despite the physical change. Rui being so attracted to his best friend without realizing it is the best kind of drama, and it makes me wonder if he was always into him before the transformation happened and everything changed
It is wild how the professor just explains the magical curse like it is a normal thing and the lack of sound effects makes the whole transformation scene feel unfinished and empty
My brain was hurting trying to understand how that drug worked but seeing Shion freak out over his new body while Rui tries to flirt with him was pretty funny in a trashy way
This show is definitely a bl at heart since they both still think of themselves as guys and the tension between them in that bedroom scene was actually kind of intense
I think the gender bender twist is hilarious because Shion was such a womanizer and now he is the one getting chased by Rui and it feels totally gay even if he looks like a girl
Rui just immediately trying to pick up his friend because he has no idea who it is makes for such a weird dynamic, especially since they were just hitting on girls together five minutes ago
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Seduced by My Best Friend
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